Acta Pharmaceutica, Vol. 68 No. 2, 2018.
Short communication, Note
https://doi.org/10.2478/acph-2018-0012
In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea
TANIA SHAMIM RIZVI
; UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman
ABDUL LATIF KHAN
; UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman
LIAQAT ALI
; UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman; Department of Chemistry, University of Sargodha, Pakistan
NARJIS AL-MAWALI
; UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman
FAZAL MABOOD
; Department of Biological Science and Chemistry, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman
JAVID HUSSAIN
; UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman; Department of Biological Science and Chemistry, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman
MUHAMMAD ADNAN
; Department of Botany, Kohat University of Science and Technology, Kohat-26000, Pakistan
AHMED AL-HARRASI
; UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman; Department of Biological Science and Chemistry, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman
Abstract
The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of C. colocynthis leaf, stem and root have higher TPC compared to those of T. apollinea. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared.
Keywords
Citrullus colocynthis; Tephrosia apollinea; oxidative stress; total phenolics
Hrčak ID:
193562
URI
Publication date:
30.6.2018.
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