Croatica Chemica Acta, Vol. 57 No. 5, 1984.
Original scientific paper
The Molecular Electrostatic Potential as a Determinant of Receptor-Drug Recognition
Dušan Hadži
; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Milan Hodošček
; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Darko Kocjan
; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Tomaž Šolmajer
; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Franc Avbelj
; Lek - Pharmaceutical and Chemical Works and Boris Kidrič Institute of Chemistry, Ljubljana, Yugoslavia
Abstract
The validity of the concept of the molecular electrostatic .
potential and its applicability in rationalizing drug-receptor interactions
are discussed on hand of examples covering the qualitative
aspects. The computational methods are briefly reviewed with
respect to economy and quality of results.
Keywords
Hrčak ID:
194073
URI
Publication date:
14.1.1985.
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