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Poikilodermatous mycosis fungoides – rare entity, different treatment modalities

Sandra Jerković Gulin orcid id orcid.org/0000-0002-1051-043X ; Department of Dermatovenereology and Infectious Diseases, General Hospital Sibenik
Romana Čeović orcid id orcid.org/0000-0002-1296-6174 ; Department of Dermatovenereology, University Hospital Center Zagreb, Salata 4, Zagreb, Croatia, University of Zagreb School of Medicine, Salata 3, Zagreb, Croatia
Ivana Ilić orcid id orcid.org/0000-0003-1988-6684 ; Department of Pathology and Cytology, University Hospital Center Zagreb and School of Medicine, Kispaticeva 12, Zagreb, Croatia
Mirna Bradamante ; Department of Dermatovenereology, University Hospital Center Zagreb, Salata 4, Zagreb, Croatia
Zrinka Bukvić Mokos ; Department of Dermatovenereology, University Hospital Center Zagreb, Salata 4, Zagreb, Croatia, University of Zagreb School of Medicine, Salata 3, Zagreb, Croatia
Kresimir Kostović ; Department of Dermatovenereology, University Hospital Center Zagreb, Salata 4, Zagreb, Croatia, University of Zagreb School of Medicine, Salata 3, Zagreb, Croatia


Puni tekst: engleski PDF 169 Kb

str. 48-48

preuzimanja: 1.199

citiraj


Sažetak

Poikilodermatous mycosis fungoides (PMF) is a rare clinical variant of early-stage MF with peculiar histological features. Poikiloderma occurs in many different clinical conditions, which makes a diagnostic procedure more complicated. PMF belongs to a group of MF variants with low risk of disease progression. We report a case of a 64-year-old woman, who presented with mottled skin aspect of erythema, poikilodermatous patches (hypopigmentation, hyperpigmentation, atrophy, and telangiectasia) on more than 80% of the body. Based on clinical, histopathological, and immunohistochemical findings, we established the diagnosis of PMF. Staging procedure determined stage IIA. As skin-directed therapy was the treatment of choice, the patient was successfully treated with psoralen-UVA (PUVA), nbUVB plus retinoid (Re-nbUVB), and PUVA plus retinoid (Re-PUVA), however, with rapid recurrence.

 

Ključne riječi

Hrčak ID:

199818

URI

https://hrcak.srce.hr/199818

Datum izdavanja:

1.5.2018.

Posjeta: 1.770 *