Croatica Chemica Acta, Vol. 91 No. 1, 2018.
Izvorni znanstveni članak
https://doi.org/10.5562/cca3266
Synthesis of Chromen-2-one, Pyrano[3,4-c]chromene and Pyridino[3,4-c]chromene Derivatives as Potent Antimicrobial Agents
Sawsan A. Fouad
; Chemistry Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt
Sadia A. Hessein
; Chemistry Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt
Samir Y. Abbas
; Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Egypt
Amel M. Farrag
; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt
Yousry A. Ammar
; Chemistry Department, Faculty of Science, Al-Azhar University (Boys), Cairo, Egypt
Sažetak
In an attempt for development of new antimicrobial agents; new series of chromen-2-one, pyrano[3,4-c]chromene and pyridino[3,4-c]chromene derivatives bearing a diazo moiety were synthesized. Chromen-2-one derivatives were synthesized via treatment of 5-(aryldiazo) salicylaldehyde with different type of active methylene derivatives. Pyrano[3,4-c]chromene and pyridino[3,4-c]chromene derivatives were synthesized via treatment of chromen-2-one derivatives with another active methylene derivatives. The synthesized compounds were evaluated for their expected antimicrobial activity; where, the majority of these compounds showed potent antibacterial and antifungal activities against the tested strains of bacteria and fungi.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Ključne riječi
Chromen-2-ones; Pyrano[3,4-c]chromenes; Pyridino[3,4-c]chromene; Antibacterial and antifungal activities
Hrčak ID:
199970
URI
Datum izdavanja:
2.1.2018.
Posjeta: 2.320 *