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Recenzija, Prikaz slučaja

Apples and their products effect on neurodegeneration and Alzheimer’s disease

Dora Babić ; Croatian Association of Nutritionists, Zagreb, Croatia
Tomislav Babić ; Polyclinic Bonifarm, Zagreb, Croatia
Saša Missoni ; Institute for anthropological research, Zagreb, Croatia

Puni tekst: engleski pdf 457 Kb

str. 181-187

preuzimanja: 571



Neurodegenerative disorders such as Alzheimer’s disease (AD) are life-threatening and an economical burden to the
health-care system. The current pharmacotherapy of AD is symptomatic and focused almost solely on cognition, with a
lot of unmet medical needs, particulary in the area of mood and behavioural symptoms. Therefore the requirement for
supportive therapy and nutritive support in the form of nutraceuticals and complex foods has been raised and numerous
studies have been conducted for the purpose of identifying the ideal nutritional compund and complex food for the support
in treatment of AD. As oxidative stress in the brain is the main symptom of AD, foods that are high in antioxidant activity
have been identified as potential nutraceuticals for AD. Due to their nutrient combination and antioxidant effect of
the nutrients, apples seem to be one of the most promisable complex foods in the nutritive support of AD. In this article
we review the potential benfit of apples on human health, combination of apple compounds and their protective effect on
neurodegeneration and AD.

Ključne riječi

Alzheimer’s disease, oxidative stress, apple, apple products, nutritive support

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