Acta Pharmaceutica, Vol. 55 No. 4, 2005.
Kratko priopćenje
Antimicrobial activity of flavonoids from Pelargonium radula (Cav.) L’Hérit
STJEPAN PEPELJNJAK
ZDENKA KALOĐERA
MARIJANA ZOVKO
Sažetak
Flavonoids from Pelargonium radula (Cav.) L'Hérit were purified by column chromatography. Two fractions were obtained: F1 (main flavonoid isoquercitrin) and F2 (main flavonoid rutin). In vitro antimicrobial activity of F1 and F2 were tested against eleven species of bacteria and eleven species of fungi. Both fractions demonstrated strong inhibitory activity against Staphylococcus aureus, Proteus rettgeri, Candida tropicalis and Microsporum gypseum. Staphylococcus sp. (coagulase-negative) and Candida lusitaniae were strongly inhibited only by fraction F1 and Fusarium graminearum only by fraction F2.
Ključne riječi
Pelargonium radula; antimicrobial activity; flavonoids; rutin; isoquercitrin; well-diffusion method; dilution method
Hrčak ID:
19049
URI
Datum izdavanja:
1.12.2005.
Posjeta: 3.151 *