Izvorni znanstveni članak
Evaluation of ear, nose and throat involvement in pemphigus vulgaris in comparison with pemphigus severity scoring systems: a cross-sectional study
Aslı Bilgic Temel
; Beysehir State Hospital
Ismail Cem Temel
Asli Bostanci Toptas
Murat Turhan
Selen Bozkurt
Soner Uzun
Sažetak
Pemphigus vulgaris (PV) frequently affects the mucous membranes of the ear, nose, and throat (ENT). Since ENT examination is not a routinely performed procedure, the exact involvement of PV remains unrecognized. The available severity scoring systems (Pemphigus Disease Area Index (PDAI) and Autoimmune Bullous Skin Disorder Intensity Score (ABSIS)) for PV do not include a full ENT examination. This study was designed to evaluate the real extent of PV in ENT areas and to find out the specific scores which indicate the need for ENT examination. The patients were evaluated for ENT manifestations by endoscopic examination whether or not they exhibited symptoms. PDAI, ABSIS, and ENT scores were calculated, and the results were compared for correlation and significance. The mucosal involvement was more severe when scored by ENT examination than when assessed by PDAI or ABSIS. The ENT score was significantly associated with symptoms and endoscopic findings, especially when PDAI ≥15 and/or ABSIS ≥17. ENT endoscopic examination could result in more accurate grading in PV. In particular, performing such an examination should be considered in patients, especially when PDAI ≥15 and/or ABSIS ≥17, regardless of ENT symptoms.
Ključne riječi
pemphigus; ear, nose and throat; PDAI (pemphigus disease area index); ABSIS (autoimmune bullous skin disorder intensity score); disease severity
Hrčak ID:
215846
URI
Datum izdavanja:
17.1.2019.
Posjeta: 821 *