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Recurrent invasive meningococcal disease in a patient with complement deficiency: a case report

Vedran Stevanović orcid id orcid.org/0000-0002-8456-6276 ; Zavod za infektivne bolesti djece, KLinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb
Branko Miše ; Zavod za infektivne bolesti djece, KLinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb


Puni tekst: engleski pdf 446 Kb

str. 53-56

preuzimanja: 412

citiraj


Sažetak

Most cases of invasive meningococcal disease occur in immunocompetent children and young adults. Serogroup B accounts for most cases in Europe followed by serogroup C, while serogroups Wand Y are uncommon. We describe a case of recurrent invasive meningococcal disease (IMD) caused by two different serogroups in a 16-year-old boy with complement deficiency. All tested cultures were negative, but PCR from blood was positive in both episodes. Our patient gradually recovered without sequelae. This case report emphasizes also the need to provide appropriate chemoprohylaxis and/or immunoprophylaxis to certain individuals.

Ključne riječi

recurrent invasive meningococcal disease; polymerase chain reaction (PCR); chemoprohylaxis; immunoprophylaxis

Hrčak ID:

216303

URI

https://hrcak.srce.hr/216303

Datum izdavanja:

28.1.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.520 *