Stručni rad

Clinical use of non-steroidal anti-inflammatory drugs in dogs

Ozren Smolec ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Maša Pita ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Frane Božić ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Jelena Šuran ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Marija Lipar ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Marko Pećin ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Bojan Toholj ; Poljoprivredni fakultet Univerziteta u Novom Sadu, Novi Sad, Srbija
Ena Oster ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Niko Ivkić ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Petra Dmitrović ; Veterinarski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska

Sažetak

Thisarticlepresentsanoverviewofthe clinical use of non-steroidal anti-inflammatory drugs (NSAID) in dogs. NSAIDs are widely used in veterinary orthopaedic patients, most commonly in the perioperative period, as well as in the long-term treatment of osteoarthritis. The adverse effects of this particular group of drugs are mainly associated with either direct or indirect damaging effects on the digestive system, kidneys and liver. With the development of new COX-2 selective NSAID-s, these adverse effects are largely minimalized. This article compares the currently available NSAIDs, and provides guidance for their usage. Very little research has been done on NSAIDs and dogs already suffering from gastrointestinal, liver or kidney diseases. Therefore, the owner’s written consent is preferred before starting NSAID therapy in such dogs. The authors also advise that other, safer therapies be used in such patients, whenever possible.

Ključne riječi

NSAID; cyclooxygenase; osteoarthritis; adverse effects

Hrčak ID:

223823

URI

https://hrcak.srce.hr/223823

Datum izdavanja:

25.3.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.615 *