Cardiologia Croatica, Vol. 14 No. 7-8, 2019.
Izvorni znanstveni članak
https://doi.org/10.15836/ccar2019.159
Causes of Elevated Troponin in Patients with Normal Coronary Angiography
Ana Reschner Planinc
; Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Maja Strozzi
; Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Zoran Miovski
; Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Kristina Marić Bešić
; Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Joško Bulum
; Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Sažetak
Troponin elevation usually indicates myocardial cell injury. However, elevated values of
troponin are not always a consequence of infarction or ischemia. The aim of this study was to elucidate
the diverse etiologies of elevated troponin in patients with normal coronary angiography. There were
947 patients at the Zagreb University Hospital Centre identified from the catheterization database who
underwent coronary angiography in 2014 due to suspected acute coronary syndrome. We identified 32
(3.38%) patients who had an alternative cause for myocyte injury other than coronary artery disease,
defined as coronary artery lumen stenosis above 30%. The elevation of cardiac troponin T (cTnT) in
patients with normal coronary angiography was found to be the consequence of diverse etiologies, including
hypertensive heart disease, Takotsubo syndrome, supraventricular tachycardia, myocarditis,
and dilated cardiomyopathy, to name a few. Apart from acute coronary syndrome, cTnT can be elevated
in a number of different conditions, which should be considered according to clinical presentation, and
that could still reflect myocardial necrosis even in the absence of significant coronary artery disease.
Ključne riječi
cardiac troponin; coronary artery disease; normal coronary angiography; myocardial cell injury
Hrčak ID:
226608
URI
Datum izdavanja:
17.9.2019.
Posjeta: 9.268 *