Skoči na glavni sadržaj

Acta clinica Croatica, Vol. 58. No. 3., 2019.

Izvorni znanstveni članak

https://doi.org/10.20471/acc.2019.58.03.02

FACTORS ASSOCIATED WITH PERSISTENCE OF HPV GENITAL INFECTION IN A SMALL COHORT OF ROMANIAN WOMEN

Irina Huică orcid id orcid.org/0000-0002-3338-7841 ; Molecular Virology Department, St. S. Nicolau Institute of Virology, Bucharest, Romania
Iulia Virginia Iancu orcid id orcid.org/0000-0002-2703-6586 ; Molecular Virology Department, St. S. Nicolau Institute of Virology, Bucharest, Romania
Anca Botezatu ; Molecular Virology Department, St. S. Nicolau Institute of Virology, Bucharest, Romania
Adriana Pleşa orcid id orcid.org/0000-0003-4566-5543 ; Molecular Virology Department, St. S. Nicolau Institute of Virology, Bucharest, Romania
Demetra Socolov ; Grigore T. Popa University of Medicine and Pharmacy, Iasi, Cuza Voda Obstetrics and Gynecology Clinical Hospital, Iasi, Romania
Sergiu Teleman ; Grigore T. Popa University of Medicine and Pharmacy, Iasi, Cuza Voda Obstetrics and Gynecology Clinical Hospital, Iasi, Romania
Gabriela Anton ; Molecular Virology Department, St. S. Nicolau Institute of Virology, Bucharest, Romania

Puni tekst: engleski pdf 316 Kb

str. 410-416

preuzimanja: 397

citiraj

Sažetak

The aim of the study was to assess the role of behavioral factors in persistence of human papillomavirus (HPV) genital infection. Out of a cohort of 605 women included in a study of HPV infection prevalence, 142 HPV positive women (aged 18-57) were retested after a 12-month
interval. None of the patients underwent surgical treatment during that period. Selected patients were asked for a second smear for cytologic analysis and HPV genotyping. A questionnaire that included information regarding reproductive health, sexual activity and smoking status was filled-in. After 12 months, 46 of 142 (32.39%) women had persistent HPV infection, with genotypes 16 and 18 found in 27 cases. On the other hand, 17 of 142 (11.97%) women had acquired new infections replacing the baseline genotypes. In our study, smoking (OR=2.320, p=0.0330) and sexual behavior (OR=5.333, p=0.0180 for more than three sexual partners; OR=2.427, p=0.0238 for cases where the partner was involved in another sexual relationship) were associated with viral persistence, while long-term contraception did not yield statistically significant results.

Ključne riječi

Papillomavirus infections; Sexual behavior; Surveys and questionnaires; Romania

Hrčak ID:

230052

URI

https://hrcak.srce.hr/230052

Datum izdavanja:

1.9.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.258 *