Acta clinica Croatica, Vol. 58. No. 3., 2019.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2019.58.03.03
MEAN PLATELET VOLUME: AN OVERLOOKED HERALD OF MALIGNANT THYROID NODULES
Mustafa Sit
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Gulali Aktas
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Bahri Ozer
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Mehmet Zahid Kocak
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Edip Erkus
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Hayri Erkol
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Semih Yaman
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Haluk Savli
; Abant Izzet Baysal University Hospital, Department of Internal Medicine, Golkoy, Bolu, Turkey
Sažetak
Physicians and surgeons pay much attention to evaluating thyroid nodules due to the malignant potential of these growths. Inflammation has a crucial role in the development of cancer. Increase in the mean platelet volume (MPV) has been described in various inflammatory conditions. Since some of thyroid nodules are malignant, we aimed to compare MPV values between patients with malignant and benign thyroid nodules after precise pathologic diagnosis. We retrospectively
analyzed hemograms of patients having undergone thyroid surgery for thyroid nodule between January 2013 and January 2015, and compared them to those recorded in healthy subjects. MPV was higher in the malignant thyroid nodule group than in the benign nodule group (9.1±1 fL vs. 7.8±0.8 fL). The difference was statistically significant (p<0.001). Increased MPV should be considered as an assistive diagnostic tool in differentiating malignant and benign thyroid nodules. However, further
prospective studies are required to confirm its usefulness in this population.
Ključne riječi
Thyroid nodule; Neoplasms; Inflammation; Mean platelet volume; Blood cell count
Hrčak ID:
230054
URI
Datum izdavanja:
1.9.2019.
Posjeta: 3.335 *