Acta clinica Croatica, Vol. 58. No. 4., 2019.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2019.58.04.09
Histopathologic Findings in Women Undergoing Hysteroscopic Resection of Endometrial Polyps and Uterine Myomas
Hrvojka Soljačić Vraneš
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ivka Djaković
orcid.org/0000-0003-2275-6389
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Marija Vrljičak
; School of Medicine, University of Rijeka, Rijeka, Croatia
Nives Đurić Orsag
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Krunoslav Kuna
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Zdenko Kraljević
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Tanja Leniček
; Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ivan Brlečić
; Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Sažetak
The aim of our study was to determine the prevalence of endometrial premalignant and malignant lesions in women undergoing hysteroscopy and to identify anthropologic factors related to the presence of malignancy. Data on 3470 women with submucosal myomas or endometrial polyps suspected on ultrasound were retrospectively analyzed. Hysteroscopy was performed in all these women in order to make a more precise diagnosis. Histologic analysis of endometrial samples obtained during hysteroscopy was used to confirm the diagnosis. Statistical analysis was performed using the SPSS 20.0.0 software. The mean age of study women was 49.1±13.3 years. The number of procedures performed due to the referral diagnosis of endometrial or submucosal myoma significantly increased over the 16-year study period. A significantly higher number of women had a benign
histopathologic diagnosis. Histologic analysis revealed malignancy in 67 women. The youngest woman and oldest woman with malignant findings was aged 32 and 75, respectively. A significantly higher
number of women with atypical hyperplasia and malignancy were in menopause. A comparable number of women with different histologic findings lived in urban and rural areas. There were a significantly larger proportion of widows among women with the histologic diagnosis of atypical hyperplasia or malignancy. The prevalence rate of malignancy in women having undergone hysteroscopy for polyps and myoma found by ultrasound was 1.93%. Postmenopausal status and older age were associated with an increased risk of malignancies, but premalignant changes and malignancies were also found in young and premenopausal women. Therefore, diagnostic hysteroscopy can be recommended in women of all age groups.
Ključne riječi
Polyps; Myoma; Ultrasonography; Uterine neoplasms; Female; Hysteroscopy
Hrčak ID:
235152
URI
Datum izdavanja:
1.12.2019.
Posjeta: 3.690 *