Sažetak sa skupa

https://doi.org/10.15836/ccar2020.54

“De-novo DCB-only” in complex coronary interventions and chronic total occlusion percutaneous coronary intervention

Mihajlo Kovačić orcid.org/0000-0002-2577-9474 ; Čakovec County Hospital, Čakovec, Croatia
Dario Dilber orcid.org/0000-0002-0062-4708 ; Čakovec County Hospital, Čakovec, Croatia

Sažetak

Introduction: Drug-coated balloon (DCB, PACCOCATH® technology) is recognized from 2014 ESC Guidelines on myocardial revascularization in treatment of DES/BMS ISR (IA recommendation)1 and its indications are expanding. DCB in “de-novo” lesions is validated mostly in Small Vessel Disease (PEPCAD I, PICCOLETO, BASKET-SMALL 2, International SVD Register). Information on Large Vessel Disease are scarce and based on preparation of the lesion with DCB followed with BMS implantation: PEPCAD IV and OCTOPUS I, PEPCAD V (Bifurcations), DEBAMI (Acute Myocardial Infarction) and PEPCAD CTO, but “de-novo DCB–only” concept is still practically “off label”.2 Available conclusions on “de-novo DCB-only” concept can be drawn from the World-wide “all comer” Registry and single center studies such as Potsdam Heart Center, trials such as OCTOPUS II (Stabile CAD), DCB Bifurcation Study (Side Branch Treatment), study on Primary Percutaneous Coronary Intervention3 and works of Kleber and coworkers which studied Late Lumen Enlargement in DCB-only concept, but again, mainly in small vessels. “De-novo DCB-only” in complex coronary interventions is practically “off label”, especially in CTO PCI. In this paper we present a complex PCI based on “de-novo DCB-only” concept and a novel approach to CTO PCI based on this method.
Case 1: 85-years-old female patient was admitted due to acute coronary syndrome. Diffuse coronary disease was found, occlusion of LCx, CTO of ostial PD. Heart team decided for PCI. Procedure was done via bilateral radial approach with support of dual lumen microcatheter, and AWE technique. Final angioplasty (Figure 1) was done with DCB 3.0x30 Sequent Please NEO (B. Braun).
Case 2: 78-years-old male patient with multiple previous PCIs was admitted for elective PCI of in-stent restenosis CTO of OM1. Previously, ostial lesion of OM2 was also p treated with DCB. CTO procedure was done via right transradial approach with support of microcatheter and AWE technique. Final procedure (Figure 2) was done with 2 DCBs covering ostial and distal OM1, and 1 DES covering fractured microcatheter tip.
Case 3: 78-years-old male patient with multiple comorbidities and previously done CABG was admitted for elective PCI after verification of vein grafts degeneration. CTO PCI of LAD (Figure 3) was done with AWE technique and finalized with angioplasty with DCB 2.0x30.
Case 4: 85-years-old male patient was admitted for elective PCI CTO of RCA. Procedure was done via left transradial approach and single guiding catheter. AWE technique was done, after which CTO body was treated with DCBs 2.0x25 and 2.5x25 and mid segment of the RCA was treated with DES 2.75x33 (Figure 4).
Case 5: 78-years-old female patient was admitted for elective PCI CTO of LAD. Procedure was done with AWE technique, and finalized with two DCBs, 2.0x30 in mid and 2.5x30 in distal segment of the LAD, and 1 DES at the bifurcation of LAD-D1 (Figure 5). Figure 5. Angiogram before and after the procedure.
Conclusion: “De-novo DCB-only” concept in complex coronary interventions in chronic coronary syndrome as well as in the setting of primary PCI shows promising results, especially for ostial lesions and by simplifying bifurcations techniques without compromising final result. Concept of de-novo DCB-only CTO procedure depicted here, with “true to-true crossing” and optimal lesion preparation, shows excellent results, but follow-up and further studies are warranted.

Ključne riječi

drug-coated balloon; complex percutaneous coronary interventions, chronic total occlusion

Hrčak ID:

236212

URI

https://hrcak.srce.hr/236212

Datum izdavanja:

26.3.2020.

Posjeta: 684 *