Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2019.60.33
Malignant brain neoplasms incidence and mortality trends in Croatia from 2001 to 2014
Goran Mrak
; Department of Neurosurgery, Clinical Hospital Center Zagreb, University of Zagreb School of Medicine Zagreb, Croatia
Valerija Korent
; Department of General Internal Medicine, Gastroenterology, Internistic Oncology, and Hematology, County Hospital Čakovec, Čakovec, Croatia
Ana Mišir Krpan
; Department of Oncology, Clinical Hospital Center Zagreb, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
Andrija Bitunjac
; Division of Surgery, GeneralHospital Dr. Josip Benčević,Slavonski Brod, CroatiaDepartment of Neurosurgery,
Martina Štenger
; Department of Pediatric Surgery, Children`s Hospital Zagreb, Croatia
Anton Kordić
; Department of Neurosurgery, Clinical Hospital Center Zagreb, University of Zagreb School of Medicine Zagreb, Croatia
Hrvoje Barić
; Department of Neurosurgery, Clinical Hospital Center Zagreb, University of Zagreb School of Medicine Zagreb, Croatia
Mario Šekerija
orcid.org/0000-0001-7508-1501
; Croatian National Cancer Registry Division for Epidemiology and Prevention of Noncommunicable Chronic Diseases, Croatian Institute of Public Health, Zagreb, Croatia
Sažetak
Aim To analyze the sex-specific incidence and mortality
trends of brain malignancies in Croatia from 2001 to 2014.
Methods Incidence and mortality rates per 100 000 population
were calculated using data obtained from the Croatian
National Cancer Registry and the Croatian Bureau of
Statistics. Rates were age-standardized to the European
Standard Population, and trends were assessed using joinpoint
regression.Results In the observed period there were 6634 new
brain malignancy cases (52% men) and 5379 deaths due
to this diagnosis (52% men). Age-standardized incidence
rates ranged from 9.2-11.5 per 100 000 in men and from
7-8.8 per 100 000 in women. Mortality rates ranged from
7.5-8.7 per 100 000 in men and from 5-6.5 in women. Incidence
trends in men, mortality in men, and mortality in
women were not statistically significant, while a significant
trend was observed in incidence in women (annual percent
change -1.5; 95% confidence interval -2.3 to -0.6). No
joinpoints were observed in any of the joinpoint analyses
by sex for incidence and mortality. Age-specific incidence
and mortality rates in both sexes indicate a trend shift toward
older age. The proportion of morphologically verified
cases ranged from 40.2%-62.4% in men and from 38.6%-
56.3% in women; the proportion of death-certificate-only
cases ranged from 3.3%-9.4% in men and from 3.3%-17.5%
in women.Conclusion Incidence and mortality of brain malignancies
in Croatia are among the highest in Europe, while reporting
on brain malignancies is still poor. There is a need for
improved care of patients with brain malignancies and detailed
and accurate data reporting.
Ključne riječi
Hrčak ID:
239732
URI
Datum izdavanja:
15.2.2019.
Posjeta: 832 *