Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2019.60.265
Influence of oxygen enriched gases during decompression on bubble formation and endothelial function in self-contained underwater breathing apparatus diving: a randomized controlled study
Ivana Šegrt Ribičić
; Department of Pulmonary Diseases, University Hospital Center Split, Split, Croatia
Maja Valić
; Department of Neuroscience University of Split School of Medicine, Split, Croatia
Joško Božić
; Department of Pathophysiology University of Split School of Medicine, Split, Croatia
Ante Obad
; Department of Health Studies University of Split, Split, Croatia
Duška Glavaš
; Department of Internal Medicine University of Split School of Medicine, Split, Croatia
Igor Glavičić
; Department of Marine Studies, University of Split, Split, Croatia
Zoran Valić
; Department of Physiology, University of Split School of Medicine, Split, Croatia
Sažetak
Aim To assess the effect of air, gas mixture composed of
50% nitrogen and 50% oxygen (nitrox 50), or gas mixture
composed of 1% nitrogen and 99% oxygen (nitrox 99)
on bubble formation and vascular/endothelial function
during decompression after self-contained underwater
breathing apparatus diving.
Methods This randomized controlled study, conducted in
2014, involved ten divers. Each diver performed three dives
in a randomized protocol using three gases: air, nitrox 50,
or nitrox 99 during ascent. The dives were performed on
three different days limited to 45 m sea water (msw) depth
with 20 min bottom time. Nitrogen bubbles formation
was assessed by ultrasound detection after dive. Arterial/
endothelial function was evaluated by brachial artery flow
mediated dilatation (FMD) before and after dive. Results Nitrox 99 significantly reduced bubble formation
after cough compared with air and nitrox 50 (grade 1 vs
3 and vs 3, respectively, P = 0.026). Nitrox 50 significantly
decreased post-dive FMD compared with pre-dive FMD
(3.62 ± 5.57% vs 12.11 ± 6.82% P = 0.010), while nitrox 99 did
not cause any significant change.
Conclusion Nitrox 99 reduced bubble formation, did not
change post-dive FMD, and decreased total dive duration,
indicating that it might better preserve endothelial function
compared with air and nitrox 50 dive protocols.
Ključne riječi
Hrčak ID:
240093
URI
Datum izdavanja:
15.6.2019.
Posjeta: 741 *