Veterinarski arhiv, Vol. 90 No. 3, 2020.
Kratko priopćenje
https://doi.org/10.24099/vet.arhiv.0623
The effect of propylene glycol and glycerol on carbohydrate and lipid metabolism in rabbits - short communication
Robert Kupczyński
; Department of Environmental Hygiene and Animal Welfare, Faculty of Biology and Animal Science, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland
Michał Bednarski
; Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland
Tomasz Piaseck
; Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland
Sažetak
This study examined the effects of glycogenic precursors (propylene glycol and glycerol) on lipid and carbohydrate metabolism of rabbit does fed a restricted diet. The study included 48 females of the Hyplus genetic line, divided into primiparous and multiparous groups. On the 4th day of the restricted diet, the rabbits were orally administered propylene glycol (PG) or glycerol (G), 2 mL/kg body weight0.75. Blood samples were collected immediately prior to administration of the glycogenic precursors and 30, 60, 90, 180, and 360 minutes thereafter. Serum concentrations of glucose, non-esterified fatty acids (NEFA), and β-hydroxybutyric acid were determined. Following the use of both glycogenic precursors, glucose concentration increased after 30 min., which was maintained until the end of the experiment. A significant (P<0.01) decrease in NEFA occurred 120 min after PG was given to primiparous and multiparous does, and remained low up to 360 min after administration. For glycerol, the decrease in NEFA occurred later after 360 min. The mean glucose concentration for the whole period was lower in multiparous females, and higher in primiparous ones. We revealed that both propylene glycol and glycerol showed the evident effect of lipolysis inhibition and gluconeogenesis stimulation, which can be used in practice (e.g. lactation, reproduction).
Ključne riječi
rabbit; metabolic status; propylene glycol; glycerol
Hrčak ID:
241827
URI
Datum izdavanja:
22.7.2020.
Posjeta: 1.468 *