Kratko priopćenje

https://doi.org/10.24869/psyd.2020.210

THE AUDITORY N1 IN SCHIZOPHRENIA: COMPARATIVE ANALYSIS WITH A MONOAURAL STIMULI PARADIGM

António Mota ; Department of Audiology, School of Health, Polytechnic of Porto, Porto, Portugal; Specsavers Hear Care, Portsmouth, United Kingdom
David Tomé ; Department of Audiology, School of Health, Polytechnic of Porto, Porto, Portugal; Neurocognition Group, Laboratory of Psychosocial Rehabilitation, Porto, Portugal; Brain Research Institute (BRI), Porto, Portugal
Carlos Campos ; Neurocognition Group, Laboratory of Psychosocial Rehabilitation, Porto, Portugal; Department of Occupational Therapy, School of Health, Polytechnic of Porto, Porto, Portugal
Nuno Rocha ; Department of Occupational Therapy, School of Health, Polytechnic of Porto, Porto, Portugal

Sažetak

The auditory N1 component has been gaining interest as a possible biomarker in schizophrenia (SCZ). N1 to right (RE) and left ear (LE) amplitudes and latencies were assessed using a monoaural auditory oddball paradigm in 12 SCZ subjects and 15 matched healthy controls (M=40.1±8.53 and 39.4±7.73, respectively). T-student test revealed no differences between RE and LE stimulation for N1 amplitude and latency to both groups. However, there were differences in peak-to-peak N1 amplitudes between the two groups for both LE (t=-3.067; ρ=0.003) and RE (t=-2.794; ρ=0.007). These findings strengthen auditory N1 has an electrophysiological biomarker for schizophrenia.

Ključne riječi

auditory N1; schizophrenia; monoaural stimuli; AERPs; biomarker

Hrčak ID:

242358

URI

https://hrcak.srce.hr/242358

Datum izdavanja:

13.8.2020.

Posjeta: 452 *