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Acta clinica Croatica, Vol. 59. No. 2., 2020.

Review article

https://doi.org/10.20471/acc.2020.59.02.18

Brucellosis in Pregnancy: Case Reports with Different Outcomes in an Endemic Region

Mile Bosilkovski orcid id orcid.org/0000-0003-0182-4741 ; Medical Faculty, Ss Cyril and Methodius University, Skopje, Republic of Macedonia
Marjan Stojovski ; Medical Faculty, Ss Cyril and Methodius University, Skopje, Republic of Macedonia; University Hospital of Obstetrics and Gynecology, Skopje, Republic of Macedonia
Dijana Siskova ; Department of Infectious Diseases, Shtip Medical Center, Shtip, Republic of Macedonia
Aleksandar Ridov ; Department of Infectious Diseases, Kavadarci Medical Center, Kavadarci, Republic of Macedonia
Emilija Kostoska ; Department of Infectious Diseases, Prilep Medical Center, Prilep, Republic of Macedonia
Kiril Krstevski ; Faculty of Veterinary Medicine, Ss Cyril and Methodius University, Skopje, Republic of Macedonia

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Abstract

Different outcomes of brucellosis in pregnancy regarding the fetus/neonate and the mother are described. Medical records of five pregnant women with brucellosis were retrospectively analyzed. Patients were treated in several departments of infectious diseases in the Republic of Macedonia between 1995 and 2009. The diagnosis of brucellosis was based on clinical findings compatible with the disease supported by detection of specific antibodies. Pregnancy outcomes in patients were as follows: spontaneous abortion, intrauterine fetal death, premature delivery in two cases (one with twin pregnancy) and term delivery. One of the women experienced relapse. Follow-up results of
neonates showed no infection and their normal growth and development. Brucellosis, especially if acquired in early pregnancy, can have an impact on pregnancy outcome. In endemic regions, in pregnant
women with persisting fever and unspecific manifestations one should always have in mind brucellosis. In these areas, cases with unexplained spontaneous abortion, intrauterine fetal death and premature delivery should also be investigated for brucellosis.

Keywords

Abortion; Brucellosis; Intrauterine fetal death; Pregnancy; Preterm labor; Term labor

Hrčak ID:

243693

URI

https://hrcak.srce.hr/243693

Publication date:

1.6.2020.

Article data in other languages: croatian

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