Professional paper
A Comparative Study of Antibacterial and Antifungal Efficacy of Soft Contact Lens Disinfecting Solutions
Tomislav Kuzman
Rajko Pokupec
Miro Kalauz
Jelena Juri
Zdenko Bujger
Aleksandra Presečki
Abstract
The aim of this study was to compare antibacterial and antifungal efficacy of five soft contact lens disinfecting solutions. The following solutions were tested: Oxysept Comfort (Advanced Medical Optics), Nitilens One Step (Avizor), Opti-Free Express (Alcon Laboratories), Complete Moisture Plus (Advanced Medical Optics) and Nitilens All-in-one (Avizor). Their efficacy to disinfect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) and Staphylococcus epidermidis (isolated from our laboratory) was tested. All study solutions reduced concentrations of bacteria and fungi below 1000 CFU/mL (reduction by 3 log and 1 log, respectively) after 8-hour overnight disinfection. However, there were differences in their disinfecting efficacy. Generally, all contact lens care solutions showed good disinfecting activity against the bacteria and fungi tested. Yet, the differences recorded in their antimicrobial activity may become more evident among non-compliant patients, and therefore the results of the study might be valuable when selecting appropriate solutions for contact lens wearers.
Keywords
Contact lens; Disinfection; Multipurpose contact lens solution, antimicrobial
Hrčak ID:
22765
URI
Publication date:
1.4.2008.
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