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Syntheses in the 4-Substituted Thiosemicarbazide Series

M. Tišler ; Institute of Organic Chemistry, Technical Faculty, University of Ljubljana, Slovenia, Yugoslavia


Puni tekst: engleski pdf 7.510 Kb

str. 147-154

preuzimanja: 231

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Sažetak

In connection with the investigations of tuberculostatic activity of arylthiosemicarbazides and arylthiosemicarbazones new 4-substituted thiosemicarbazides (I-XVIII) were synthesized. Condensation of these with aldehydes or ketones afforded the corresponding 4-substituted thiosemicarbazones (XIX-LVI). The attempted 'acetylation of p-nitrobenzaldehyde-4-phenylthiosemicarbazone and o - chlorobenzaldehyde - 4 - phenylthiosemicarbazone gave besddes acetanilide N,N.-diacetyl-p-nitrobenzylidenhydrazine (LVII) ,and N,N-dia cetyl-chlorobenzylidenehydrazine (LIX) .The 4-substituted thiosemic arbazides and thiosemiearbazones were tested for their tuberculostatic activity.

Ključne riječi

Hrčak ID:

246841

URI

https://hrcak.srce.hr/246841

Datum izdavanja:

7.11.1956.

Posjeta: 666 *