Review article
https://doi.org/10.3325/cmj.2020.61.139
How to face the aging world – lessons from dementia research
Dinko Mitrečić
orcid.org/0000-0003-4836-1721
; Laboratory for Stem Cells, Department of Histology and Embryology, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia
Dražen Juraj Petrović
; Genos d.o.o., Zagreb, Croatia
Paula Stančin
; Omnion Research International d.o.o., Zagreb, Croatia
Jasmina Isaković
; Omnion Research International d.o.o., Zagreb, Croatia
Barbara Zavan
; Department of Medical Sciences, University of Ferrara, Ferrara, Italy
Gerardo Tricarico
; Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy
Mirjana Kujundžić Tiljak
; Andrija Štampar School of Public Health University of Zagreb, School of Medicine, Zagreb, Croatia
Monica Di Luca
; European Brain Council, Brussels, Belgium
Abstract
A continuous rise in life expectancy has led to an increase
in the number of senior citizens, now amounting to a fifth
of the global population, and to a dramatic increase in the
prevalence of diseases of the elderly. This review discuss-
es the threat of dementia, a disease that imposes enor-
mous financial burden on health systems and warrants
efficient therapeutic solutions. What we learned from nu-
merous failed clinical trials is that we have to immediately
take into account two major elements: early detection of
dementia, much before the onset of symptoms, and per-
sonalized (precision) medicine treatment approach. We
also discuss some of the most promising therapeutic di-
rections, including stem cells, exosomes, electromagnetic
fields, and ozone.
Keywords
Hrčak ID:
253153
URI
Publication date:
14.6.2020.
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