Stručni rad

https://doi.org/10.21860/medflum2021_371663

Diabetes type 1 and pregnancy outcome at University Hospital Center Split – a retrospective study

Doris Praprotnik orcid.org/0000-0002-8536-0675 ; Clinical Department of Obstetrics and Gynecology, University Hospital Center Split, Croatia
Damir Roje ; Clinical Department of Obstetrics and Gynecology, University Hospital Center Split, Croatia
Maja Radman ; Clinical Department of Endocrinology and Diabetes, University Hospital Center Split, Croatia
Marko Vulić ; Clinical Department of Obstetrics and Gynecology, University Hospital Center Split, Croatia
Zoran Meštrović ; Clinical Department of Obstetrics and Gynecology, University Hospital Center Split, Croatia

Sažetak

Abstract. Aim: To evaluate the prevalence, assessment, and perinatal outcome of pregnancies complicated with diabetes mellitus type 1 (DM type 1) at a tertiary perinatal center in the town of Split, Dalmatia County. Materials and methods: The investigation was designed as a retrospective cohort study. All pregnant women with DM type 1 that were supervised and gave birth at Clinical Department of Obstetrics and Gynecology, Split University Hospital Center during a 7-year period (2009-2015), including those diagnosed in 2015 and having delivered in 2016, were included in the study group. Data were collected by the census method from legal protocol books. Control group included DM type 1-free pregnancies entered in the same protocol books just following a particular study woman, if meeting all inclusion and exclusion criteria. Results: There were 70 DM type 1 pregnancies, accounting for 0.2% of all deliveries. DM type 1 group newborns were statistically heavier (3650±605 vs. 3428±591g; p=0.031), more frequent large for gestational age (24.3% vs. 5.7%; p=0.002) and macrosomic (24.3% vs. 10%; p=0.033). Compared to control group, DM type 1 women had a significantly higher delivery rate in the 37th to 39th week of gestation (84.3% vs. 58.6%; p=0.001) and higher cesarean section rate (61.4% vs. 32.9%; p=0.001). Conclusion: DM type 1 significantly influences perinatal outcome. It requires multidisciplinary approach and complete supervision should be provided at specialized centers. Respecting the fetal origin of adult diseases theory, inappropriate protocol(s) and/or individual decision(s) can have many health consequences throughout newborns life, which highlights DM type 1 pregnancies to a public health level issue.

Ključne riječi

cesarean section; diabetes mellitus; fetal macrosomia; pregnancy

Hrčak ID:

255667

URI

https://hrcak.srce.hr/255667

Datum izdavanja:

1.6.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.837 *