Infektološki glasnik, Vol. 41 No. 1, 2021.
Stručni rad
https://doi.org/10.37797/ig.41.1.2
Clinical Manifestations of Bartonella henselae Infection Among Children: A Single Centre Study
Ivana Valenčak-Ignjatić
orcid.org/0000-0003-1523-1031
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Diana Didović
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Ante Šokota
orcid.org/0000-0002-1038-4787
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Laura Prtorić
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Vedran Stevanović
orcid.org/0000-0002-8456-6276
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Oktavija Đaković Rode
orcid.org/0000-0001-8023-4314
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska; Stomatološki fakultet Sveučilišta u Zagrebu, Hrvatska
Marija Gužvinec
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Branko Miše
; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska; Medicinski fakultet Sveučilišta u Zagrebu, Hrvatska
Sažetak
Objectives: The aim of this study was to analyze clinical manifestations, epidemiology and laboratory parameters of B. henselae infection among children treated at the University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb from January 2014 until June 2019.
Materials and methods: We retrospectively analyzed the epidemiology, clinical and laboratory characteristics among children with positive indirect immunofluorescence assay for B. henselae IgM and IgG or positive B. henselae polymerase chain reaction from lymph node aspirate.
Results: A total of 104 patients, 47 (45,1%) female and 57 (54,8%) male were enrolled. The median age was 9,7 (range, 1,1 to 17,3 years). A history of cat contact was present in 101 (97,1%) children. Acute infection was serologically confirmed in 87 (83,6%), in 5 (4,8%) with PCR while both methods were positive in 12 (11,5%) patients. The presentation on B. henselae infection were regional lymphadenopathy, disseminated disease, encephalopathy and fever of unknown origin. Suppurative inflammation was the most common complication in patients with lymphadenopathy 12/92 (13%). Full recovery was the most frequent outcome (96,1%).
Conclusion: B. henselae infection among children is usually a mild disease presented as regional lymphadenopathy. Serology and polymerase chain reaction are useful tests for diagnosis. Treatment duration and choice of therapy depend on clinical manifestation and developed complications.
Ključne riječi
cat scratch disease; Bartonella henselae; children; lymphadenopathy; abscess; fever; encephalopathy
Hrčak ID:
259101
URI
Datum izdavanja:
18.6.2021.
Posjeta: 3.033 *