Kratko priopćenje

https://doi.org/10.2478/acph-2022-0013

Chemical composition, antioxidant, antimicrobial and antiviral activities of the leaf extracts of Syzygium myrtifolium

MUSTAFFA ALBAKRI AHMAD ; Department of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman, Bandar Barat, 31900 Kampar, Perak, Malaysia
YI HUI LIM ; Department of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman, Bandar Barat, 31900 Kampar, Perak, Malaysia
YIK SIN CHAN ; Department of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman, Bandar Barat, 31900 Kampar, Perak, Malaysia
CHUN-YUAN HSU ; Department of Bioscience Technology, College of Science, Chung Yuan Christian University, Chung Li District, Taiwan 32023, R.O.C.
TZONG-YUAN WU ; Department of Bioscience Technology, College of Science, Chung Yuan Christian University, Chung Li District, Taiwan 32023, R.O.C.
NAM WENG SIT orcid.org/0000-0002-5949-491X ; Department of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman, Bandar Barat, 31900 Kampar, Perak, Malaysia

Sažetak

This study was conducted to evaluate the chemical composition and biological activities of the leaf extracts of Syzygium myrtifolium Walp. (Myrtaceae). The results indicate that the leaf extracts of S. myrtifolium contain various classes of phytochemicals (alkaloids, anthraquinones, flavonoids, phenolics, saponins, tannins and triterpenoids) and possess antioxidant, antibacterial, antifungal and antiviral activities. Ethyl acetate, ethanol, methanol, and water extracts exhibited significantly higher (p <0.05) oxygen radical absorbance capacity and ferric reducing antioxidant power than the hexane and chloroform extracts. However, all extracts exhibited stronger inhibitory activity against four tested species of yeasts (minimal inhibitory concentration: 0.02–0.31 mg mL–1) than against six tested species of bacteria (minimal inhibitory concentration: 0.16–1.25 mg mL–1). The ethanolic extract offered the highest protection of Vero cells (viability >70 %) from the cytopathic effect caused by the Chikungunya virus while the ethyl acetate extract showed significant replication inhibitory activity against the virus (p <0.001) using the replicon-enhanced green fluorescent protein reporter system.

Ključne riječi

Syzygium myrtifolium leaf; antibacterial; antifungal; antioxidant; Chikungunya virus; recombinant baculovirus

Hrčak ID:

262130

URI

https://hrcak.srce.hr/262130

Datum izdavanja:

30.6.2022.

Posjeta: 1.221 *