Izlaganje sa skupa
SERUM VITAMIN D AND MAGNESIUM LEVELS IN A PSYCHIATRIC COHORT
George Woodward
; University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Jonathan C. M. Wan
; University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Kiran Viswanath
; Hertfordshire Partnership University NHS Foundation Trust, UK
Rashid Zaman
; Centre for Mental Health Research in association with University of Cambridge (CMHR-CU), Cambridge, UK ;Hertfordshire Partnership University NHS Foundation Trust, UK ;Department of Psychiatry, University of Cambridge, Cambridge, UK
Sažetak
Background: Both Vitamin D deficiency and magnesium deficiency have an increased prevalence and have been associated with
an increased risk of and increased severity of symptoms in both depression and schizophrenia (Boerman 2016, Tarleton & Littenberg
2015). This effect appears more pronounced in younger populations and is often apparent from the time of initial diagnosis and is
present with adjustment for confounding factors. Thus, the evidence suggests that Vitamin D and magnesium deficiency reflects not
only dietary or somatic aspects of health but also may have a role in the pathophysiology of depression and schizophrenia.
Subjects and methods: A single site audit of serum Vitamin D and magnesium levels in patients at an Acute Day Treatment Unit
was carried out. Blood tests were performed on admission and analysed in house. Data were collected between April - June 2019
and was analysed subsequently, as described below (n=73).
Results: Our data show that our psychiatric day treatment unit cohort (n=73) had a higher proportion of vitamin D deficiency
(52%) than the general population (40%), although due to the limited sample size this was not significant (p=0.22, Chi-squared test).
The percentage of patients who were magnesium deficient was 78.6% (n=22/28). However, the F60 subgroup of patients with
personality disorders showed a high prevalence of vit D deficiency (p=0.07), highlighting a trend towards significance despite the
limited size of this subgroup.
Conclusions: We carried out a single-site audit of serum vitamin D and magnesium levels in a psychiatric day unit population in
order to assess the extent of vitamin deficiency in such patients. These data indicate that that the proportion of patients with vitamin
D deficiency is higher than in the general population. Further larger analysis is needed to establish the statistical significance of
these data and whether treatment with vitamin D supplementation improves outcomes.
Ključne riječi
psychiatry; vitamin deficiency; audit : vitamin D; magnesium
Hrčak ID:
262868
URI
Datum izdavanja:
4.9.2019.
Posjeta: 330 *