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MOZART'S MUSIC AND MULTIDRUG-RESISTANT EPILEPSY: A POTENTIAL EEG INDEX OF THERAPEUTIC EFFECTIVENESS

Chiara Bedetti ; Istituto Serafico, Assisi, Perugia, Italy
Patrizia D’Alessandro ; Istituto Serafico, Assisi, Perugia, Italy
Massimo Piccirilli ; Istituto Serafico, Assisi, Perugia, Italy; Department of Experimental Medicine, University of Perugia, Perugia, Italy
Moreno Marchiafava ; Istituto Serafico, Assisi, Perugia, Italy
Antonella Baglioni ; Istituto Serafico, Assisi, Perugia, Italy
Marta Giuglietti ; Istituto Serafico, Assisi, Perugia, Italy
Domenico Frondizi ; Neurophysiopathology Division, Department of Neuroscience, Santa Maria Hospital, Terni, Italy
Marina Menna ; Istituto Serafico, Assisi, Perugia, Italy
Sandro Elisei ; Istituto Serafico, Assisi, Perugia, Italy; Department of Philosophy, Social and Human Sciences and Education, University of Perugia, Perugia, Italy


Puni tekst: engleski pdf 128 Kb

str. 567-571

preuzimanja: 257

citiraj


Sažetak

Multidrug-resistant epilepsy is a pathological condition that affects approximately one-third of patients with epilepsy, especially
those with associated intellectual disabilities. Several non-pharmacological interventions have been proposed to improve quality of life of these patients. In particular, Mozart’s sonata for two pianos in D major, K448, has been shown to decrease interictal electroencephalography (EEG) discharges and recurrence of clinical seizures in these patients. In a previous study we observed that in institutionalized subjects with severe/profound intellectual disability and drug-resistant epilepsy, a systematic music listening protocol reduced the frequency of seizures in about 50% of cases. This study aims to assess electroencephalography as a quantitative (qEEG) predictive biomarker of effectiveness of listening to music on the frequency of epileptic discharges and on background rhythm frequency (BRF).

Ključne riječi

Mozart effect; EEG; music; drug; resistant epilepsy

Hrčak ID:

262999

URI

https://hrcak.srce.hr/262999

Datum izdavanja:

21.11.2018.

Posjeta: 1.055 *