Izlaganje sa skupa

SUICIDALITY IN TREATMENT RESISTANT DEPRESSION: PERSPECTIVE FOR KETAMINE USE

Katarzyna Jakuszkowiak-Wojten ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Maria Gałuszko-Węgielnik ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Alina Wilkowska ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Jakub Słupski ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Adam Włodarczyk ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Natalia Górska ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Joanna Szarmach ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Łukasz P. Szałach ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Mariusz S. Wiglusz ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland
Krzysztof Krysta ; 2Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Wiesław Jerzy Cubała ; Department of Psychiatry, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland

Sažetak

Suicidal ideations or attempts in patients with major depressive disorder (MDD) are emergent conditions that require immediate
treatment. Numerous therapeutic interventions to reduce suicide risk in psychiatric disorders are effective in long-term suicide
prevention, but there is necessity of sufficient, rapid pharmacological treatment of suicidal risk in MDD.
Ketamine, an N-methyl-D-aspartate (NMDA) antagonist, has been reported to have rapid antidepressant effect. Depressive
symptoms, anxiety, hopelessness, suicidal ideation had decreased within hours after ketamine infusion. Ketamine’s rapid symptoms
relief and reduction of suicide thoughts has aroused growing interests in psychiatric association.

Ključne riječi

ketamine; NMDA; glutamate; suicidal ideation; depression

Hrčak ID:

263311

URI

https://hrcak.srce.hr/263311

Datum izdavanja:

4.9.2019.

Posjeta: 501 *