Izlaganje sa skupa
RISK FACTORS FOR NONCOMPLIANCE WITH ANTIPSYCHOTIC MEDICATION IN LONG-TERM TREATED CHRONIC SCHIZOPHRENIA PATIENTS
Marek Krzystanek
; Department of Rehabilitation Psychiatry, Medical University of Silesia, Katowice, Poland
Krzysztof Krysta
; Department of Rehabilitation Psychiatry, Medical University of Silesia, Katowice, Poland
Małgorzata Janas-Kozik
; Developmental Age Clinical Ward, Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland ; John Paul II Pediatric Center, Sosnowiec, Poland
Ewa Martyniak
; Department of Rehabilitation Psychiatry, Medical University of Silesia, Katowice, Poland
Janusz Rybakowski
; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
Sažetak
Background: The attitudes of schizophrenic patients toward medications directly impact the treatment compliance. Although
noncompliance represents a serious concern in long-term schizophrenia treatment, a detailed information on the factors that impair
compliance is still limited. The present study aims to assess the factors related to noncompliance with antipsychotics agents, in longterm
treated chronic paranoid schizophrenia patients.
Subjects and methods: Two groups of such patients (total number n=162) were analyzed and compared: 1). patients with
symptomatic remission on haloperidol (n=32), clozapine (n=40) or olanzapine (n=45), and 2). drug resistant patients (n=45). The
mean duration of the disease was 19.3 years.
Results: Altogether, in our patient sample, a better drug attitude was found in the olanzapine and clozapine groups. Our findings
have also revealed that worse attitude toward antipsychotics correlated with an earlier onset of schizophrenia, younger patient age,
shorter duration of the disease, higher burden of symptoms, treatment with a typical antipsychotics, and higher severity of akathisia.
Conclusion: Our results suggest that detecting factors that influence the patient’s attitude toward medications might be helpful
for designing targeted educational strategies in chronic schizophrenia patients (particularly those with the high risk of
noncompliance), and further trials are warranted to explore this topic.
Ključne riječi
schizophrenia; compliance; drug attitude; antipsychotics; long-term treatment
Hrčak ID:
264170
URI
Datum izdavanja:
4.9.2019.
Posjeta: 346 *