Izlaganje sa skupa
DEPRESSION AND DRY EYE DISEASE: A NEED FOR AN INTERDISCIPLINARY APPROACH?
Thomas J. M. Weatherby
; Churchill College, Cambridge, UK
Venkat Ram Vasant Raman
; University College London, London, UK
Mark Agius
; Centre for Mental Health Research in Association with The University of Cambridge, Cambridge, UK
Sažetak
A recent meta-analysis including data from 22 studies including 2.9 million patients found that anxiety and depression are more
prevalent in patients with dry eye disease (DED) than in controls. DED is a common disorder of the tear film which can cause ocular
irritation, foreign body sensation and visual disturbance. However there is often a great discrepancy between signs and symptoms of
DED, which the symptoms often being more associated with non-ocular disorders such as depression and PTSD than to tear film
parameters. In this way it could be considered as more of a psychiatric than ophthalmic complaint. DED and depression feedback on
one another in a synergistic manner. Severity of DED is associated with symptoms of anxiety and depression. Treatment of DED
could help reduce depression symptoms, but also effective management of depression could help alleviate symptoms of DED.
Complicating this however is the evidence that SSRIs can exacerbate DED. This makes the management of these comorbidities more
difficult, however there are putative therapeutic targets which may be a source of future treatments for DED-associated depression.
In conclusion, it is clear that DED and depression are closely linked and influence one another in ways that drastically affect
patients’ lives. Collaboration between psychiatrists and ophthalmologists could be beneficial in the management of those with DED.
Ključne riječi
depression; dry eye disease; multidisciplinary care
Hrčak ID:
264210
URI
Datum izdavanja:
4.9.2019.
Posjeta: 472 *