Conference paper
SYMPTOM FREQUENCY CHARACTERISTICS OF THE HAMILTON DEPRESSION RATING SCALE OF MAJOR DEPRESSIVE DISORDER IN EPILEPSY
Mariusz S. Wiglusz
; Department of Psychiatry, Medical University of Gdańsk, Poland
Jerzy Landowski
; Department of Psychiatry, Medical University of Gdańsk, Poland
Lidia Michalak
; Regional Epilepsy Outpatient Unit, Copernicus Hospital, Gdańsk, Poland
Wiesław J. Cubała
; Department of Psychiatry, Medical University of Gdańsk, Poland
Abstract
Background: Depressive disorders are common among patients with epilepsy (PWE). The aim of this study was to explore
symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) and recognize the clinical characteristics of Major
Depressive Disorder in PWE.
Subjects and methods: A sample of 40 adults outpatients with epilepsy and depression was diagnosed using SCID-I for DSM-IVTR
and HDRS-17. The total HDRS-17 score was analysed followed by the exploratory analysis based on the hierarchical model.
Results: The frequencies of HDRS-17 items varied widely in this study. Insomnia related items and general somatic symptoms
items as well as insomnia and somatic factors exhibited constant and higher frequency. Feeling guilty, suicide, psychomotor
retardation and depressed mood showed relatively lower frequencies. Other symptoms had variable frequencies across the study
population.
Conclusions: Depressive disorders are common among PWE. In the study group insomnia and somatic symptoms displayed
highest values which could represent atypical clinical features of mood disorders in PWE. There is a need for more studies with a
use of standardized approach to the problem.
Keywords
major depressive disorder; depressive disorders,; epilepsy; HDRS; factor analysis
Hrčak ID:
264499
URI
Publication date:
8.9.2015.
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