Izlaganje sa skupa
IMPACT OF OLANZAPINE ON COGNITIVE FUNCTIONS IN PATIENTS WITH SCHIZOPHRENIA DURING AN OBSERVATION PERIOD OF SIX MONTHS
Adam Klasik
; Institute of Psychology, University of Opole, Poland
Krzysztof Krysta
; Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Marek Krzystanek
; Department of Psychiatry and Psychotherapy, Medical University of Silesia, Katowice, Poland
Katarzyna Skałacka
; Institute of Psychology, University of Opole, Poland
Sažetak
Objective: The objective of our study was to evaluate the effect of olanzapine treatment on selected cognitive functions in patients
suffering from schizophrenia during an observation period of six-months.
Subjects and methods: Twenty patients with a diagnosis of schizophrenia according to ICD-10 criteria for research were
examined. One day before initiation of olanzapine a baseline assessment was performed. The neuropsychological examination was
repeated 28 days, 60 days, 3 months, and 6 months after the beginning of treatment. Cognitive function measurements were
performed using Signal, COGNITRON and RT tests, being a part of the computer-based Vienna Test System (VTS).
Results: Our study showed an improvement in the assessed cognitive functions. Impairments in cognitive domains were observed
at baseline as compared to published normative data, and enhancement in achieved results was observed subsequently in all stages
of the treatment until the 6th month.
Conclusion: The above results are consistent with a number of other studies on the impact on cognitive functioning in patients
with schizophrenia treated with olanzapine.
Ključne riječi
olanzapine; schizophrenia; cognitive processes; attention; reaction time
Hrčak ID:
264677
URI
Datum izdavanja:
1.9.2011.
Posjeta: 256 *