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NEUROBIOLOGY OF BIPOLAR DISORDER - LESSONS FROM MIGRAINE DISORDERS

Janathon Holland ; University of Cambridge School of Clinical Medicine, UK
Mark Agius ; Department of Psychiatry University of Cambridge, UK ; South Essex Partnership University Foundation Trust, UK


Puni tekst: engleski pdf 239 Kb

str. 162-165

preuzimanja: 122

citiraj


Sažetak

Treatment for Bipolar Affective Disorder is at present largely empirical, in the lack of a definitive understanding of the
biological basis of the condition. Many theories have been proposed regarding the underlying neurobiology. These have included
aetiologies relating to altered neurotrophic factor expression, mitochondrial endoplasmic reticulum dysfunction with related calcium
changes, and loss of inhibitory interneurons. Here an attempt is made to integrate such current understanding, in part by
considering the changes observed in migraine - a condition which has a number of similarities with bipolar disorder.

Ključne riječi

migraine; bipolar disorder; depressive disorders

Hrčak ID:

264849

URI

https://hrcak.srce.hr/264849

Datum izdavanja:

1.9.2011.

Posjeta: 280 *