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https://doi.org/10.21860/medflum2021_264902

The types of delivery and components of metabolic syndrome among patients with schizophrenia without therapy

Sergej Nadalin ; Odjel za psihijatriju, Opća bolnica “Dr. Josip Benčević”, Slavonski Brod, Hrvatska
Sanja Dević Pavlić orcid id orcid.org/0000-0001-8440-1722 ; Zavod za medicinsku biologiju i genetiku, Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Vjekoslav Peitl ; Klinika za psihijatriju, Klinički bolnički centar Sestre milosrdnice, Zagreb, Hrvatska; Hrvatsko katoličko sveučilište, Medicinski fakultet, Zagreb, Hrvatska
Dalibor Karlović ; Klinika za psihijatriju, Klinički bolnički centar Sestre milosrdnice, Zagreb, Hrvatska; Hrvatsko katoličko sveučilište, Medicinski fakultet, Zagreb, Hrvatska
Lena Zatković ; Bolnička ljekarna, Klinički bolnički centar Rijeka, Rijeka, Hrvatska
Alena Buretić-Tomljanović ; Zavod za medicinsku biologiju i genetiku, Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska


Puni tekst: hrvatski pdf 2.510 Kb

str. 437-443

preuzimanja: 110

citiraj


Sažetak

Aim: Delivery via caesarean section is repeatedly associated with an increased risk for components of metabolic syndrome among individuals from the general population, while data for patients with schizophrenia are scarse and contradictory. In this study, we aimed to investigate whether, and to what extent, the type of delivery contributes to body mass index (BMI) values and lipid and glucose concentrations among two groups of patients with schizophrenia without therapy: first-episode patients (N = 48), and chronic patients, nonadherent to antipsychotic medications (N = 83). Patients and methods: Information regarding antipsychotic nonadherence and type of delivery was obtained from anamnestic and heteroanamnestic data. Plasma total cholesterol, LDL cholesterol (low density lipoprotein cholesterol), HDL cholesterol (high density lipoprotein cholesterol), triglyceride and glucose levels were determined after a 12-hour fasting period. Results: The prevalence of delivery via caesarean section was 8.4 %. Triglyceride concentrations were significantly higher among patients born via cesarean section than among patients born via vaginal delivery 1.5 (0.6 – 4.3) vs. 1.1 (0.3 – 3.1); z = -2.21, p = 0.027. Type of delivery contributes by approximately 3.3 % to triglyceride concentration variability. Conclusions: Our results indicate that type of delivery influences to a smaller extent plasma triglyceride concentration among patients with schizophrenia without medication. Delivery via caesarean section represents a risk factor for increased triglyceride concentrations.

Ključne riječi

body mass index, caesarean section, glucose, lipids, schizophrenia

Hrčak ID:

264902

URI

https://hrcak.srce.hr/264902

Podaci na drugim jezicima: hrvatski

Posjeta: 328 *