Izvorni znanstveni članak
https://doi.org/10.26332/seemedj.v5i2.205
Blood Group and COVID-19 Transmission and Mortality in Patients With Malignant Disease
Senar Ebinç
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Zeynep Oruç
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Ziya Kalkan
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Zuhat Urakçı
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Muhammet Ali Kaplan
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Mehmet Küçüköner
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Abdurrahman Işıkdoğan
; Department of Medical Oncology, Dicle university, Diyarbakır, Turkey
Sažetak
Aim: The study aimed to investigate risk factors affecting the transmission of and mortality from COVID-19 in patients diagnosed with a malignant disease. In this context, ABO blood groups, gender, age, type of malignant disease, type of anti-tumoral agents, comorbidities and stage were examined.
Materials and Methods: Files of 1,256 patients who presented to our clinic between March and December 2020 were retrospectively reviewed. Patients diagnosed with a malignant disease who became infected with COVID-19 and those who did not were compared with regard to demographic, clinical characteristics and laboratory results (status of having been infected with COVID-19, ABO blood groups).
Results: Of 1256 patients in total, 72 (5.7%) were diagnosed with COVID-19. Median age of cancer patients infected with COVID-19 was 53 years (18-80). The most common types of cancer included gastrointestinal cancer (22.2%), breast cancer (20.8%), genitourinary cancer (20.8%) and lung cancer (16.7%). Of the patients diagnosed with COVID-19, 18.1% (n=13) died. Multivariate analysis identified disease stage as an independent prognostic factor for the risk of mortality [HR: 0.07, 95% CI (0.007-0.74), (p=0.02)]. A comparison of patients who became infected with COVID-19 and those who did not with regard to ABO blood groups (p=0.39) showed no statistically significant differences between the two groups. There was also no correlation between ABO blood groups and the risk of COVID-19-related mortality (p=0.83).
Conclusion: In patients suffering from malignant diseases, the ABO blood type exhibited no correlation with the risk of COVID-19 transmission and mortality. This study determined the presence of metastatic disease as a negative prognostic factor. Patients suffering from a metastatic malignant disease represent a high risk group for COVID-19 and should be treated using all necessary precautions.
Ključne riječi
COVID-19; abo blood group system; neoplasm
Hrčak ID:
265868
URI
Datum izdavanja:
26.11.2021.
Posjeta: 430 *