Izvorni znanstveni članak
TYPE OF CELL SEPARATOR, FENWAL AMICUS VS FRESENIUS COM TEC, MAY INFLUENCE THE CORPUSCULAR ELEMENTS VALUE OF THE DONOR`S BLOOD
Elvedin Landzo
; Institute of Transfusion Medicine F B&H, Sarajevo, Bosnia and Herzegovina
Izeta Aganovic-Musinovic
; Immunology Department, Medical Faculty of University in Sarajevo, Sarajevo, Bosnia and Herzegovina
Danijel Bevanda
; Department of Internal Medicine, University Hospital Mostar, Mostar, Bosnia and Herzegovina
Ante Bogut
; Department of Internal Medicine, University Hospital Mostar, Mostar, Bosnia and Herzegovina
Mateo Bevanda
; Center for Urgent Medicine, University Hospital Mostar, Mostar, Bosnia and Herzegovina
Daniela Bevanda Glibo
; Department of Internal Medicine, University Hospital Mostar, Mostar, Bosnia and Herzegovina
Danijel Pravdić
; Department of Internal Medicine, University Hospital Mostar, Mostar, Bosnia and Herzegovina
Sažetak
ntroduction: During the plateletpheresis procedure the number of thrombocytes in the donor’s blood significantly decreases,
and the levels of the hematocrit (HCT), hemoglobin (Hgb), and leukocyte (WBC) diminish as well. Influence of the cell separator is
one of the factors that affects the levels of HCT, Hgb and WBC. In this study, the goal was to determine the value difference o f HCT,
Hgb, WBC, and platelets after the platelet pheresis process between performance on Fenwal AMICUS and on Fresenius Com Tec.
Donors and methods: The criteria for participation: male in the age range of 25-45. We have formed two groups: for both
groups - 180 separations were performed on 60 participants were the values of hematocrits, concentration of hemoglobin and
number of leukocytes were established before and after separation using the double-needle continuous flow cell separation (DN-
CFCS) on two different devices, Fenwal AMICUS device and the Fresenius Com Tec. device. To confirm the statistical differences
we have used Student t-test for independent or dependent samples, as well as Mann-Whitney U test as non-parametric alternative. To
compare differences between the values of four parameters (P1-P2) from two groups (using two devices - Fenwal AMICUS and
Fresenius Com Tec) The possibility of errors were accepted for Į<0.05, and the difference between groups as statistical relevant
were accepted for p<0.05.
Results Statistically significant lower values were noted for all researche d parameters after separation on both devices. The
statistically significant average values for Hct, Hgb and WBC obtained between two devices, were less than 0.05 (p=0.05).
For the platelets (Plt) there was no statistical significant difference (p>0.05 - Į=0.05), between average level obtained using
either Fenwal AMICUS or Frazenius Com Tec.
Conclusion: The type of cell separator had the influence on the decrease value of the observed parameters.
Ključne riječi
Comparison Fenwal AMICUS and Frazenius Com Tec; plateletpheresis; donor hematological value
Hrčak ID:
269465
URI
Datum izdavanja:
21.12.2019.
Posjeta: 337 *