Izlaganje sa skupa
EUROTROPISM AND NEUROPSYCHIATRIC SYMPTOMS IN PATIENTS WITH COVID-19
Patrizia Moretti
; Department of Psychiatry, University of Perugia, Perugia, Italy
Francesca Brufani
Valentina Pierotti
Giorgio Pomili
Agata Di Buo
Cecilia Giulietti
Filippo Masini
Vivjana Tanku
Massimo Claudio Bachetti
Giulia Menculini
Alfonso Tortorella
Sažetak
Background: The Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory
Syndrome-CoronaVirus-2 (SARS-CoV-2). Beyond the most common clinical features of COVID-19, mainly represented by
respiratory symptoms, other systems may be interested by the infection. Among these, through a neurotropic pathway, the central
nervous system (CNS) may be affected by the virus, leading to developing neuropsychiatric symptoms. Particularly, this study
focuses on neurological symptoms determined by the Sars-CoV-2 infection, as well as on the underlying pathogenetic processes.
Methods: For the present review, we followed a narrative approach. A literature search was carried out concerning the
neurological consequences of COVID-19. Papers were screened, focusing on the clinical manifestations interesting the CNS and on
their possible role in the early diagnosis of the disease.
Results: We display the most significant neurological clinical manifestations of COVID-19. Common neurological manifestations
(ageusia, anosmia, and encephalitis) are first described. Subsequently, we provide a focus on delirium and its possible pathoge netic
and clinical correlates. Delirium is not only a possible resultant of the COVID-19 neurotropism, but it may also be precipitated by a
number of environmental factors that assume further relevance during the pandemic.
Conclusions: Neuropsychiatric symptoms, and particularly delirium, can help identifying the infection at an early stage. Tailored
treatments should be identified in order to prevent complications.
Ključne riječi
neurotropism; delirium; SARS-CoV-2; COVID-19
Hrčak ID:
270200
URI
Datum izdavanja:
4.12.2021.
Posjeta: 263 *