Izvorni znanstveni članak

https://doi.org/10.20471/acc.2021.60.03.10

Clinical and Microbiological Assessment of Non-Surgical Treatment of Chronic Periodontitis in Controlled and Uncontrolled Type 2 Diabetic Patients

Jelena Mirnić orcid.org/0000-0001-9637-8419 ; University of Novi Sad, Faculty of Medicine, Department of Periodontology and Oral Medicine, Novi Sad, Serbia
Milanko Đurić ; University of Novi Sad, Faculty of Medicine, Department of Periodontology and Oral Medicine, Novi Sad, Serbia; Dentistry Clinic, Novi Sad, Serbia
Nađa Nikolić ; Department of Human Genetics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia
Tanja Veljović ; University of Novi Sad, Faculty of Medicine, Department of Periodontology and Oral Medicine, Novi Sad, Serbia
Ivana Gušić ; University of Novi Sad, Faculty of Medicine, Department of Periodontology and Oral Medicine, Novi Sad, Serbia; Dentistry Clinic, Novi Sad, Serbia
Đorđe Petrović ; University of Novi Sad, Faculty of Medicine, Department of Periodontology and Oral Medicine, Novi Sad, Serbia; Dentistry Clinic, Novi Sad, Serbia
Jelena Milašin ; Department of Human Genetics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia

Sažetak

Chronic periodontitis is a common complication in diabetes. The aim of this study
was to evaluate some clinical and microbiological parameters in controlled and uncontrolled type 2
diabetes mellitus (type 2 DM) patients compared to non-diabetic (NDM) individuals, as well as to
assess the effect of non-surgical periodontal therapy on these parameters. The study was performed in
61 type 2 DM patients with periodontitis (group 1A: 29 patients having achieved good metabolic
control, HbA1c <7%; group 1B: 32 patients with poor metabolic control, HbA1c ≥7%), and 31 NDM
individuals suffering from periodontitis. Periodontal indices (plaque index, PI; gingival index, GI;
probing pocket depth, PPD; and clinical attachment level, CAL) were measured and subgingival
plaque samples were analyzed using polymerase chain reaction prior to treatment initiation and 3
months post-treatment. The results recorded on the majority of measured parameters indicated that
differences in treatment success achieved in the three treatment groups were not statistically significant
(ΔPI p=0.646; ΔGI p=0.303; and ΔCAL p=0.233). Likewise, comparison of the effectiveness in
microorganism reduction revealed no significant differences between DM groups and NDM patients.
Therefore, study results supported the hypothesis that periodontal therapy outcome was unaffected by
the level of glycemic control in patients with diabetes.

Ključne riječi

Diabetes mellitus; Periodontal disease/therapy; Glycosylated hemoglobin (HbA1c); Polymerase chain reaction

Hrčak ID:

271435

URI

https://hrcak.srce.hr/271435

Datum izdavanja:

1.9.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.692 *