Veterinarska stanica, Vol. 54 No. 1, 2023.
Izvorni znanstveni članak
https://doi.org/10.46419/vs.54.1.3
Total antioxidant status of bitches before and after ovariectomy
Tugomir Karadjole
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ljerka Fučkala
; Ministarstvo poljoprivrede, Uprava za sigurnost hrane, Republike Hrvatske, Hrvatska
Ljiljana Bedrica
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Nino Maćešić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Goran Bačić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ivan Folnožić
orcid.org/0000-0002-8988-0862
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Branimira Špoljarić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Juraj Šavorić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ivan Butković
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Nikica Prvanović Babić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Maša Efendić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Miroslav Tomić
; KBC Sestre Milosrdnice, Zagreb, Hrvatska
Vesna Sokol Karadjole
; KBC Zagreb, Hrvatska
Sandra Kunštek
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Martina Lojkić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Sažetak
Surgery impairs homeostasis, which is manifested in immunological, neuroendocrine, and metabolic changes in the organism. It is assumed that the response of the organism is proportional to the extent of the operative injury. Accordingly, the aim of this study was to determine the antioxidant status of bitches before and after ovariectomy. Fifteen bitches were presented to the Clinic for Reproduction and Obstetrics, Faculty of Veterinary Medicine, Zagreb, for elective ovariectomy due to castration. Blood sampling was performed on Day 0 (before surgery) and on Days 1, 3 and 7 after surgery to measure total antioxidant status (TAS), complete blood count, biochemistry and CRP. Total antioxidant capacity was determined using TAS test kits. For the purpose of standardisation of reference values of TAS in laboratory, 30 serum samples of healthy, intact bitches were also analysed and the mean value +/- two standard deviations was used as the reference value. The average reference value was 1.55 mmol/L. The values of total antioxidant capacity after surgery on all sampling days did not differ significantly. Comparing the minimum and maximum values on all sampling days, there were no statistical differences in the values of the total antioxidant capacity in ovariectomised bitches. Based on these results, it can be concluded that ovariectomy did not cause oxidative stress.
Ključne riječi
ovariectomy; bitch; total antioxidant status
Hrčak ID:
273744
URI
Datum izdavanja:
25.5.2022.
Posjeta: 870 *