Veterinary Archives, Vol. 92 No. 1, 2022.
Original scientific paper
https://doi.org/10.24099/vet.arhiv.1199
Electroencephalographic manifestations during propofol and xylazineketamine anaesthesia in goats
Mrigakshi Yadav
; Department of Veterinary Physiology and Biochemistry, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, Uttarakhand, India
Sunil K. Rastogi
; Department of Veterinary Physiology and Biochemistry, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, Uttarakhand, India
Arup K. Das
; Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, Uttarakhand, India
Malini Pant
; Department of Veterinary Physiology and Biochemistry, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, Uttarakhand, India
Arun K. Madan
; Department of Veterinary Physiology, College of Veterinary Sciences and Animal Husbandry, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalya Evam Go Anusandhan Sansthan (DUVASU), Mathura, Uttar Pradesh, India
Ruokuobeinuo Huozha
; Department of Veterinary Physiology and Biochemistry, College of Veterinary and Animal Sciences, GBPUAT, Pantnagar, Uttarakhand, India
Abstract
The use of intravenous anaesthesia for short term surgical procedures in animal husbandry practices is increasing.
However, information on the quality of an anaesthetic regime in goats has remained inadequate. Therefore,
electroencephalographic studies were conducted on twelve apparently healthy adult female Barbari crossbred goats,
aged 2 to 4 years, to assess the anaesthetic quality of a propofol and xylazine-ketamine combination. Quantitative
analysis of EEG parameters [Total power, Median Frequency, Spectral Edge Frequency 90 (SEF-90) and Relative
Power (RP) of different frequency bands delta (δ), theta (θ), alpha (α) and beta (β)] were assessed pre-experimentally
(control), and at one, five, 10, 30 min, one hr, and two hr after intravenous propofol (4 mg/kg) and xylazine (0.05
mg/kg)-ketamine (4 mg/kg) administration. After propofol and xylazine-ketamine administration total power, RP-δ
and θ increased significantly (P<0.05) while SEF 90, MF, RP-α and RP-β decreased. Most of the EEG changes
were adequately depicted in vertex and parietal channels. Spectral analysis of EEG tracings suggested that propofol
produced minimum anaesthetic stress and is a safer and better choice for short term anaesthesia in goats.
Keywords
anaesthesia; electroencephalography; goat; propofol; xylazine-ketamin
Hrčak ID:
274812
URI
Publication date:
24.3.2022.
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