Izlaganje sa skupa
OLEH HORNYKIEWICZ (1926-2020): SIXTY YEARS SINCE THE PIONEERING L-DOPA APPLICATION - ONE YEAR SINCE THE DEATH OF THE PIONEER
Omer Ć.Ibrahimagić
; Department of Neurology, University Cinical Centre Tuzla, Tuzla, Bosnia and Herzegovina
Anamaria Tadić
; MVZ Dermatologie und Asthetik Saarland, Saaarbrucken, Gemany
Suljo Kunić
orcid.org/0000-0001-7900-1222
; Department of Neurology, Primary Health Care Center Tuzla, Tuzla, Bosnia and Herzegovina
Dževdet Smajlović
; Department of Neurology, University Cinical Centre Tuzla, Tuzla, Bosnia and Herzegovina
Zikrija Dostović
; Department of Neurology, University Cinical Centre Tuzla, Tuzla, Bosnia and Herzegovina
Amra Iljazović
; Department of Neurology, University Cinical Centre Tuzla, Tuzla, Bosnia and Herzegovina
Sažetak
Oleh Hornykiewicz was born on November 17, 1926 in Lamberg, Ukraine. After completing his studies in July 1951, he moved to
"Pharmacological Institute of the University of Vienna". In 1958, he started his research on centrally acting drugs at the same
institute and came up with the idea of linking laboratory observations with animals with the basal ganglia of the human brain. Soon,
Hornykiewicz initiated a new question: L-DOPA as a therapy for Parkinson's disease? Fortunately, after administration of this new
drug, patients were able to perform motor activities which could not be prompted to any comparable degree by any known drug. In
the following decades, initial fiction became an unavoidable fact. Dopamine, adapted and combined with carbidopa or benzerazide,
has evolved into a drug that no longer recognizes the borders of countries and continents. Distinguished emeritus prof. Oleh
Hornykiewicz died on May 26, 2020 at the age of 93 in Vienna, Austria. Unfortunately, despite everything he has done and deserved,
the Nobel Prize was not received.
Ključne riječi
basal ganglia; Parkinson disease; dopamine; L-DOPA
Hrčak ID:
275419
URI
Datum izdavanja:
19.10.2021.
Posjeta: 208 *