Ostalo
Vaginal metastasis of serous ovarian adenocarcinoma - a case report
Mario Puljiz
; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Danko Velimir Vrdoljak
; Department of Surgical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Damir Danolić
; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ilija Alvir
; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Robert Zorica
; Department of Medical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Darko Tomica
; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ivica Mamić
; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Melita Perić-Balja
; Department of Clinical Pathology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ivka Djaković
; Department of Gynecology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ines Bilokapić
; Department of Gynecology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ivana Bogdan
; Department of Gynecology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Sažetak
Patients with high-grade serous carcinoma most frequently present at an advanced clinical stage and have a very poor overall survival. A characteristic feature of the disease is the absence of early phase symptomatology in many patients. Ovarian cancer spreads primarily by intraperitoneal implantation of exfoliated cancer cells, by lymphatic dissemination, and rarely by hematogenous spread. Very rarely it metastasizes to the vagina. We are reporting a case of a patient who developed a vaginal metastasis as the first sign of the disease. The patient underwent total abdominal hysterectomy with partial resection of the vagina, bilateral adnexectomy, omentectomy, pelvic and paraaortic lymphadenectomy, peritoneal biopsies, resection of the rectum with termino-terminal anastomosis and hepatectomy of the 5th and 6th segments. Pathohistological analysis confirmed the diagnosis of high-grade serous ovarian adenocarcinoma with a vaginal metastasis, cancer-free resection margins, and hepatic cystic echinococcosis as accidental finding. The patient underwent 6 cycles of adjuvant chemotherapy (paclitaxel and cisplatin). A 30-month follow-up did not reveal any relapse of the disease.
Ključne riječi
ovarian cancer; vaginal metastasis
Hrčak ID:
275973
URI
Datum izdavanja:
25.11.2012.
Posjeta: 534 *