Ostalo

Malignant spindle cell tumor – carcinoma or sarcoma?

Boris Stubljar ; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital for Tumours, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Krešimir Gršić ; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital for Tumours, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Sanda Šitić ; Department of Clinical Pathology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Marija Pastorčić-Grgić ; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital for Tumours, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Renato Janušić ; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital for Tumours, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Danijel Došen ; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital for Tumours, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Sažetak

Spindle cell carcinoma (SpCC) is a rare subvariant of upper aerodigestive tract mucosal squamous cell carcinoma.
The histological appearance of SpCC is characterized by dual composition of malignant squamous carcinoma cells and malignant sarcoma-like spindle cells. The spindle cells are not specific for SpCC, but are present in various other malignant, benign and inflammatory lesions. Subsequently, accurate pathological diagnosis of SpCC is challenging. Although there are no clear treatment guidelines, it is widely regarded that SpCC should be treated as SCC of the corresponding localization and disease stage.

Ključne riječi

spindle cell carcinoma; carcinosarcoma; collision tumor; head and neck squamos cell carcinoma

Hrčak ID:

275975

URI

https://hrcak.srce.hr/275975

Datum izdavanja:

25.11.2012.

Podaci na drugim jezicima: hrvatski

Posjeta: 647 *