Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2020.61.410
Microsurgical versus endoscopic surgery for non-functioning pituitary adenomas: a retrospective study
Tomáš Česák
; Department of Neurosurgery, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Pavel Póczoš
; Department of Neurosurgery, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Jaroslav Adamkov
; Department of Neurosurgery, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Petr Čelakovský
; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Filip Gabalec
; 4th Department of Internal Medicine, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Jiří Soukup
; The Fingerland Department of Pathology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Radka Dvořáková
; Department of Radiology, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Petr Krůpa
; Department of Neurosurgery, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Sažetak
Aim To compare microsurgical technique (mTSS) and endoscopic technique (eTSS) in the treatment of non-functioning pituitary adenomas (NFPAs).
Methods We retrospectively evaluated the charts of 50 patients who underwent either mTSS or eTSS for NFPA in the
Department of Neurosurgery, University Hospital Hradec
Kralove from 2013 to 2019. We enrolled all patients who
were not treated by postoperative adjuvant radiotherapy
and who underwent at least two regular postoperative
magnetic resonance imaging (MRI) tests. We compared
the groups in terms of the extent of resection, surgery duration, blood loss, complication rate, overall clinical effect
on the endocrinological and ophthalmological deficit, and
postoperative growth pattern of the residual tumor mass.
Results The mTSS group had significantly shorter surgical
time (75 min vs 127 min, P<0.001) and lower perioperative blood loss (156 mL vs 256 mL, P=0.027). The groups
did not significantly differ in the extent of resection, overall
clinical or hormonal effect, and the complication rate. The
extent of resection did not correlate with tumor consistency, while the tumor growth rate did not correlate with age
or Ki-67 expression.
Conclusions There was no major difference between the
approaches in surgery radicality or safeness. However, eTSS
remains the method of choice due to its potentially higher
postoperative preservation of hormonal functions
Ključne riječi
Hrčak ID:
277989
URI
Datum izdavanja:
23.10.2020.
Posjeta: 326 *