Izvorni znanstveni članak
What can we learn from studies about multiple primaries?
Irena Novosel
; Department of Pathology, Dr. Ivo Pedišić General Hospital, Sisak, Croatia
Marijana Turčić
; Ljudevit Jurak Clinical Department of Pathology , Sestre milosrdnice University Hospital, Zagreb, Croatia
Borislav Spajić
; Clinical Department of Urology, Sestre milosrdnice University Hospital, Zagreb, Croatia
Ivan Prskalo
; Teachers Faculty, University of Zagreb, Zagreb, Croatia
Ante Reljić
; Clinical Department of Urology, Sestre milosrdnice University Hospital, Zagreb, Croatia
Božo Krušlin
; Ljudevit Jurak Clinical Department of Pathology , Sestre milosrdnice University Hospital, Zagreb, Croatia
Sažetak
Simultaneity of primary renal cell carcinoma (PRCC) and second primary malignant tumors (SPMT) of other organs
is considered to be very rare.
This study was run in order to determine the incidence of SPMT in patients with PRCC.
During the period 1997-2001, 287 patients underwent surgery for PRCC. They included 196 male and 91 female patients aged 24-91 years.
SPMTs were present in 11(3.8%) out of 287 patients with PRCC and in 14 (4.9%) of tumors, respectively. The most common were SPMT of bladder (1.0%), colon (1.0%), prostate (0.7%) and skin (0.7%). Out of 14 SPMT, 8 were synchronous (57.1%), 5 subsequent (35.1%) and 1 antecedent (7.1%).
Our survey identified a patient with three simultaneous SPMTs involving the urinary bladder, the prostate and the colon.
SPMTs are not so rare in the population. Hence, the clinician should be stimulated to maintain a lifetime follow–up of patients with primary malignant disease.
Ključne riječi
kidney; primary renal cell carcinoma; second primary malignant tumors; multiple primaries
Hrčak ID:
280403
URI
Datum izdavanja:
22.11.2007.
Posjeta: 305 *