Studija slučaja
https://doi.org/10.5671/ca.46.2.9
A Rare Case Report of Non-Familial Sporadic Reoccurrence of Cherubism: Difficulties from the Surgeon’s Point of View
Vjosa Hamiti Krasniqi
; Department of Maxillofacial Surgery, Faculty of Medicine, University of Prishtina, Republic of Kosova
Mergime Prekazi-Loxha
orcid.org/0000-0001-5660-9323
; Department of Maxillofacial Surgery, Faculty of Medicine, University of Prishtina, Republic of Kosova
Zana Agani
; Department of Maxillofacial Surgery, Faculty of Medicine, University of Prishtina, Republic of Kosova
Aida Rexhepi
; Department of Maxillofacial Surgery, Faculty of Medicine, University of Prishtina, Republic of Kosova
Jehona Ahmedi
; Department of Maxillofacial Surgery, Faculty of Medicine, University of Prishtina, Republic of Kosova
David Stubljar
orcid.org/0000-0002-9653-9830
; In-Medico, Department of Research and Development, Metlika, Slovenia
Sažetak
Cherubism is a rare bone dysplasia in children characterized by symmetrical bone resorption limited only to the jaws and diagnosed as bone lesions filled with soft fibrous giant cell-rich tissue that can expand and cause severe facial deformity. Most patients have germline mutations in the gene encoding SH3BP2, a signaling adaptor protein involved in adaptive and innate immune responses. Treatment depends on the clinical course of the disease. The current case report presents a young patient with cysts in frontal region of maxilla without family history, that had recurrences of cysts, and is representing a less documented, rare case. Histological finding at that time was indicating a giant cell granuloma and later a grey tumor. Due to the existence of other pathological findings in the jaws with the presence of giant cells, we had difficulties to diagnose cherubism as surgeons.
Ključne riječi
cherubism, jaw tumors, mandibular, maxilla, case report
Hrčak ID:
280915
URI
Datum izdavanja:
30.6.2022.
Posjeta: 432 *