Pregledni rad
https://doi.org/10.20471/acc.2021.60.s3.01
False pharmacoresistance – a true problem
Silvio Bašić
; Department of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, Croatia
Ivana Marković
; Department of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, Croatia
Davor Sporiš
; Department of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, Croatia
Ivana Šušak Sporiš
; Department of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, Croatia
Filip Đerke
; Department of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, Croatia
Ivana Mrđen
; Department of Neurology, Zadar General Hospital, Zadar, Croatia
Sažetak
Pharmacoresistant epilepsy poses a great burden to patients, their families, and the
whole healthcare system, with numerous social, economic, physical, and psychical consequences.
Hence, it is a diagnosis that has to be made only in cases of high certainty, after all potential causes of
epilepsy have been evaluated. One of the important causes of pharmacoresistant epilepsy is false pharmacoresistance,
an entity that implies a condition in which poor disease control is not a consequence
of the biology of the disease itself, antiepileptic drug inefficacy, and/or patient specificity. It is a consequence
of human error and strongly depends on the experience of the treating physician, as well as on
the attitude of the patient. Despite its ‘falseness’, this entity is accompanied by real consequences for
the patient and his family, and at the same time, it delays appropriate treatment of the actual disease
from which the patient is suffering. In order to introduce appropriate treatment and avoid unnecessary
and harmful diagnostic procedures, false pharmacoresistance is a condition that has to be ruled out in
any patient with difficult-to-treat seizures.
Ključne riječi
Epilepsy; False pharmacoresistance; Antiepileptic drugs; Pharmacoresistant epilepsy
Hrčak ID:
281063
URI
Datum izdavanja:
31.12.2021.
Posjeta: 624 *