Izvorni znanstveni članak
Value of fine needle aspiration cytology in diagnosis for salivary gland lesions: our experience
Vesna Ramljak
; Department of Clinical Cytology, University Hospital for Tumors, Zagreb, Croatia
Marija Pastorčić-Grgić
; Department of Head and Neck Surgery, University Hospital for Tumors, Zagreb, Croatia
Irena Ranogajec
; Department of Clinical Cytology, University Hospital for Tumors, Zagreb, Croatia
Irena Novosel
; Department of Pathology, General Hospital “Dr Ivo Pedišić“, Sisak, Croatia
Renato Janušić
; Department of Head and Neck Surgery, University Hospital for Tumors, Zagreb, Croatia
Danijel Došen
; Department of Head and Neck Surgery, University Hospital for Tumors, Zagreb, Croatia
Sažetak
The retrospective study was designed to evaluate salivary gland lesions diagnosed in the Department of Clinical Cytology and surgically treated in the Department of Head and Neck Surgery in the University Hospital for Tumors, Zagreb, Croatia between 1990 and 2004. We analyzed localization, histological type and concordance between cytology and final histological diagnosis.
The study includes 286 patients treated for salivary gland lesions. All patients had fine-needle aspiration (FNA) cytology of the lesion before surgery. All the cytological specimens obtained were aspirated from palpable lesion or revealed during sonographic examination.
The majority of lesions was localized in the parotid gland. There were 213 benign tumors, 40 benign lesions and 33 malignant tumors. The most common benign tumors were pleomorphic adenoma and Warthin's tumor, while the most common malignant tumor was adenoid cystic carcinoma.
Our results show overall accuracy of fine-needle aspiration cytology of 91%. The sensitivity in differentiating benign from malignant lesions was 61% and specificity was 95%. The positive predictive value was 61% and negative predictive value 95%.
FNA cytology of salivary gland lesions is safe, easy to perform and valuable noninvasive method of preoperative diagnosis. It is accurate method and differentiates non-tumorous benign lesion, benign and malignant tumor, as well as grade of tumor malignancy.
Ključne riječi
salivary gland lesions; FNA cytology
Hrčak ID:
281590
URI
Datum izdavanja:
20.12.2004.
Posjeta: 295 *