Skoči na glavni sadržaj

Izvorni znanstveni članak

https://doi.org/10.26800/LV-144-supl3-1

Bacterial superinfections in critically ill COVID-19 patients – experiences from University Hospital Dubrava tertiary COVID-19 center

Maja Ćurčić ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Hani Almahariq ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Sonja Hleb ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Juraj Havaš ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Danijela Kralj Husajna ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Marko Pražetina ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Hrvoje Lasić ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Emil Dolenc ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Andrea Kukoč ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Antonija Mihelčić ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Ivan Miko ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Andrea Romić ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Danijela Tipura ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Željka Drmić ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Marcela Čučković ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Vanja Blagaj ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb
Jasminka Peršec Peršec ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb, Stomatološki fakultet Sveučilišta u Zagrebu
Andrej Šribar ; Klinika za anesteziologiju, reanimatologiju i intenzivnu medicinu, Klinička bolnica Dubrava, Zagreb, Stomatološki fakultet Sveučilišta u Zagrebu


Puni tekst: hrvatski pdf 1.801 Kb

str. 1-14

preuzimanja: 1.124

citiraj

Puni tekst: engleski pdf 1.801 Kb

str. 1-14

preuzimanja: 234

citiraj

Prilozi: 00d_SADRZAJ.pdf


Sažetak

Goal: To determine incidence of bacterial superinfections, causative pathogens demographic data, relevant laboratory parameters and outcomes in critically ill COVID-19 patients treated in primary respiratory intensivist center (PRIC) UH Dubrava. Patients and methods: In this retrospective observational study, clinical and laboratory data of 692 critically ill patients treated in PRIC UH Dubrava between March 1st 2020. and February 1st
2021. was collected using the hospital information system software (BIS) and statistical analysis was performed using the jamovi statistical package. Results: Out of 692 patients admitted to the ICU, 383 acquired bacterial or fungal superinfections. 305 acquired pneumonia, 133 bloodstream infections and 120 urinary infections. 66.3% of patients were males, and bacterial superinfections were more common in patients admitted from hospital wards or external ICUs. Out of 305 patients with pneumonia, 295 were receiving mechanical ventilation and satisfied the criteria for ventilator associated pneumonia. Patients with bloodstream infections maintained elevated neutrophil lymphocyte ratio, lymphopenia and elevated CRP levels on day 7 compared to those without BSI. Urinary infections were more common in females, and did not have an effect on outcomes. All patients that developed superinfections had prolonged ICU and hospital stay. Conclusion: Incidence of bacterial superinfections in critically ill COVID-19 patients is 55.3%. Most common infections are ventilator associated pneumonia, bloodstream infections and urinary infections. Most common pathogens are multi-drug resistant pathogens. Patients with bacterial superinfections have longer ICU and hospital stay, and in these patients, persistent elevation of NLR ratio and worsening of lymphopenia are characteristic for patients with worse outcomes.

Ključne riječi

COVID-19; INTENSIVE CARE MEDICINE; ICU; VAP; BLOODSTREAM INFECTIONS; URINARY INFECTIONS

Hrčak ID:

284129

URI

https://hrcak.srce.hr/284129

Datum izdavanja:

25.9.2022.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.299 *