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https://doi.org/10.15836/ccar2022.212

Overview of endocarditis epidemiology and management during a 7-year period – single centre experience

Siniša Roginić orcid id orcid.org/0000-0002-0384-8088
Martina Roginić orcid id orcid.org/0000-0001-5463-5392
Tereza Knaflec orcid id orcid.org/0000-0002-4915-3935
Nikolina Mijač Mikačić orcid id orcid.org/0000-0002-0933-6577
Marija Čajko
Domagoj Futivić orcid id orcid.org/0000-0003-4363-1008


Puni tekst: engleski pdf 134 Kb

str. 212-212

preuzimanja: 71

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Sažetak

Ključne riječi

infective endocarditis; epidemiology; COVID-19

Hrčak ID:

287262

URI

https://hrcak.srce.hr/287262

Datum izdavanja:

8.12.2022.

Posjeta: 228 *



Infective endocarditis is a rare but clinically underappreciated condition associated with high morbidity and mortality. We present data from 30 cases of endocarditis diagnosed and treated in our hospital during 7 years period, including COVID-19 pandemic lockdown. Demographic and clinical data were collected, including microbiological isolates, number of affected valves, perivalvular, embolic, and immunological complications, surgical outcome and mortality. Most patients were male, average age was 62 years and Enterococcus was the most frequently isolated pathogen. 17/30 patients were operated, most of them urgently due to valvular dysfunction, uncontrolled infection and/or systemic embolization. In-hospital mortality of 30% was directly associated with severity of infection and necessity for emergency and urgent surgery. Unexpected rise of incidence occurred in 2021 with 11 identified cases. We assume possible rebound effect of postponed diagnosis after COVID-19 pandemic lockdown due to restricted access to all levels of health care. Our data generally reflect literary data on incidence and prognosis of endocarditis with additional peak in incidence during 2021 and more severe clinical presentation (1-3).

LITERATURE

1 

Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, et al. ESC Scientific Document Group. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J. 2015 November 21;36(44):3075–128. https://doi.org/10.1093/eurheartj/ehv319 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/26320109

2 

Rajani R, Klein JL. Infective endocarditis: A contemporary update. Clin Med (Lond). 2020 January;20(1):31–5. https://doi.org/10.7861/clinmed.cme.20.1.1 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/31941729

3 

George A, Alampoondi Venkataramanan SV, John KJ, Mishra AK. Infective endocarditis and COVID -19 coinfection: An updated review. Acta Biomed. 2022 March 14;93(1):e2022030. https://doi.org/10.23750/abm.v93i1.10982 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/35315423


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